I retrieved the D. melanogaster CaMKII-PG sequence from FlyBase (NP_001014696.1) and used it as the query sequence for a BLASTP search of nr. The image below shows two conserved domains. The region with the deletion of six amino acids at the splice junction in D. biarmipes falls between the two conserved domains and is not well conserved in other species as seen in the alignments (not shown).
Here are the sequences from several species for a multiple alignment:
>gi|62473187|ref|NP_001014696.1| Calcium/calmodulin-dependent protein kinase II, isoform G [Drosophila melanogaster] MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHH PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPE NLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVG YPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVAS VVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGSQVKESTDSSSTTLEDDDIKEDKK GTVDRSTTVVSKEPEVNLFTNKAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEG IDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTHQSEETRVWHKRDNK WQNVHFHRSASAKISGATTFDFIPQK >gi|194913427|ref|XP_001982693.1| GG16421 [Drosophila erecta] MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHH PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPE NLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVG YPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVAS VVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGDGSQVKESTDSSSTTLEDDDIKEDKK GTVDRSTTVVSKEPEDIRILCPAKTCQQITGNSQCSSAARRQEIIKITEQLIEAINSGDFDGYTKICDPH LTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHT HQSEETRVWHKRDNKWQNVHFHRSASAKISGATTFDFIPQK >gi|195355682|ref|XP_002044319.1| GM13012 [Drosophila sechellia] MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHH PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPE NLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVG YPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVAS VVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGSQVKESTDSSSTTLEDDDIKEDKK GTVDRSTTVVSKEPEDIRILCPAKTYHQNIGNSQCSSARRQEIIKITEQLIEAINSGDFDGYTKICDPHL TAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTH QSEETRVWHKRDNKWQNVHFHRSASAKISGATTFDFIPQK >gi|194768288|ref|XP_001966244.1| GF22825 [Drosophila ananassae] MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHH PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPE NLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVG YPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVAS VVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGDGSQVKESTDSSSTTLEDDDIKEDKK AIVDRSTTVISKEPEDIRILCPAKTCQQISGSSQCSSAARRQEIIKITEQLIEAINSGDFDGYTKICDPH LTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHT HQSEETRVWHKRDNKWQNVHFHRSASAKISGATTFDFVSQK >gi|195173597|ref|XP_002027574.1| GL18383 [Drosophila persimilis] MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHH PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPE NLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVG YPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITASEALKHPWICQRERVAS VVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGDGSQVKESTDSSSTTLEDDDIKEDKK GIVDRSTTVISKEPEEIRIVCPAKTCQQISGNSQCSSARRQEIIKITEQLIEAINSGDFDGYTKICDPHL TAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTH QSEETRVWHKRDNKWQNVHFHRSASGKISGATTFDFIPQK >gi|195134014|ref|XP_002011433.1| GI14101 [Drosophila mojavensis] MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHH PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPE NLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVG YPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVAS VVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGDGSQVKESTDSSSTTLEDDDVKEDKK GIVDRSTTVISKDPEEIRIVCPAKTCQQMSGNSSQCSSARRQEIIKITEQLIEAINSGDFDGYTKICDPH LTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHT HQSEETRVWHRRDNKWQNVHFHRSASGKISGATTFDFIPQK >gi|195450704|ref|XP_002072597.1| GK13605 [Drosophila willistoni] MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHH PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPE NLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVG YPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVAS VVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGDGSQVKESTDSSSTTLEDDDVKEDKK GIVDRSTTVISKDPEEIRIVCPAKTCQQISGNSQCSSARRQEIIKITEQLIEAINSGDFDGYTKICDPHL TAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTH QSEETRVWHKRDNKWQNVHFHRSASGKISGATTFDFIPQK >gi|195402201|ref|XP_002059695.1| GJ20463 [Drosophila virilis] MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHH PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPE NLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVG YPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVAS VVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGDGSQVKESTDSSSTTLEDDDVKEDKK GIVDRSTTVISKDPEEIRIVCPAKTCQQISGTSQCSSARRQEIIKITEQLIEAINSGDFDGYTKICDPHL TAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTH QSEETRVWHRRDNKWQNVHFHRSASGKISGATTFDFMPQK >gi|195064078|ref|XP_001996492.1| GH23972 [Drosophila grimshawi] MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHH PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPE NLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVG YPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVAS VVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGDGSQVKESTDSSSTTLEDDDVKEDKK GIVDRSTTVISKDPEEIRIVCPAKTCQQISGNSQCSSARRQEIIKITEQLIEAINSGDFDGYTKICDPHL TAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTH QSEETRVWHRRDNKWQNVHFHRSASGKISGATTFDFVSQK >gi|201023361|ref|NP_001128422.1| calcium/calmodulin-dependent protein kinase II [Apis mellifera] MATPTACTRFSDNYELKEELGKGAFSVVRRCVQKSTGHEFAAKIINTKKLTARDFQKLEREARICRKLQH PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVVHRDLKPE NLLLASKAKGAAVKLADFGLAIEVQGEAQAWFGFAGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVG YPPFWDEDQHRLYAQIKTGSYDYPSPEWDTVTPEAKNLINQMLTVNPSKRITASEALKHPWICQRERVAS VVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSIITKKGDGSQVKESTDSSTTIEDDDVKEDKKG GVDRSSTVIAKEPEEIRIVCPIKTCSQLSTNSQCSARRQEIIKMTEQLIESINTGDFEAYTKICDPHLTA FEPEALGNLVEGMDFHKFYFDNVLGKNCKAVNTTILNPHVHLLGEDAACIAYVRLTQYMDKQGVAHTHQS EESRVWHKRDNKWQNVHFHRSAVTGPSPFTYNHK >gi|380011195|ref|XP_003689696.1| PREDICTED: calcium/calmodulin-dependent protein kinase type II alpha chain-like isoform 2 [Apis florea] MATPTACTRFSDNYELKEELGKGAFSVVRRCVQKSTGHEFAAKIINTKKLTARDFQKLEREARICRKLQH PNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVHHCHHNGVVHRDLKPE NLLLASKAKGAAVKLADFGLAIEVQGEAQAWFGFAGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVG YPPFWDEDQHRLYAQIKAGSYDYPSPEWDTVTPEAKNLINQMLTVNPSKRITASEALKHPWICQRERVAS VVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSIITKKGDGSQVKESTDSSTTIEDDDVKEDKKG GVDRSSTVIAKEPERIRIVCPIKTCSQLSTNSQCSARRQEIIKMTEQLIESINTGDFEAYTKICDPHLTA FEPEALGNLVEGMDFHKFYFDNVLGKNCKAVNTTILNPHVHLLGEDAACIAYVRLTQYMDKQGVAHTHQS EESRVWHKRDNKWQNVHFHRSAVTGPSPFTYNHK >gi|91079668|ref|XP_966888.1| PREDICTED: similar to Ca2+/calmodulin-dependent protein kinase II [Tribolium castaneum] MAVPIACTRFSDNYDLKEELGKGAFSVVRRCVQKSTGLEFAAKIINTKKLSARDFQKLEREARICRKLQH PNIVRLHDSIQEENFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPE NLLLASKAKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLKKEPYGKPVDIWACGVILYILLVG YPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPGKRITASEALKHPWICQRERVAS VVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSIIVKKGDGSQVKESTDSSTTLEDDDIKEDKKG GVDRSSTVIAKDPEEIRIVCPEKPYSQLSTNSQGSARRQEIIKMTEQLIEAINTGDFEAYTKICDPHLTA FEPEAMGNLVEGMDFHKFYFDNVLGKNCKAVNTTILNPHVHLLGEDAACIAYVRLTQYMDKHGQAHTHQS EESRVWHKRDNKWQNVHFHRSGGTGGAAFGFSSHK